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Identification of exposome clusters

  • 4 days ago
  • 1 min read


Title

Identification of exposome clusters based on societal, social, built and natural environment – results of the ABCD cohort study

Source

Telkmann K, Gudi-Mindermann H, Bogers R, Ahrens J, Tönnies J, van Kamp I, Vrijkotte T, Bolte G.

Environment International 2025. https://doi.org/10.1016/j.envint.2025.109335 

What

Exploratory exposome cluster identification based on 60 variables from the Social Exposome conceptual framework (enabling a holistic assessment of societal, social, built and natural environment).

The study was carried out in the Netherlands using data from the 2850 participants of the ABCD Cohort study.

Findings

·      Exposome clusters are mainly driven by socioeconomic and physical factors such as neighbourhood income and deprivation, rather than individual level social characteristics.

·      Children belonging to more socio-economically deprived clusters had worse mental health, showing the relevance of structural inequalities in poor health outcomes.

Recommendations 

This innovative exploratory statistical approach can be used to identify disadvantaged social groups, or groups of children at high risk of mental health problems within a population.

Policy interventions should address social structural inequalities, as these are drivers of poor mental health in children

Target audience

Researchers using statistical methods, health economists, policy professionals


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